Zinc Neutering

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Dr. Rob


As most of you are already aware, Dr. Michael and I have serious reservations about the long term health ramifications of spaying and neutering dogs (in particular spaying and neutering before maturation is complete).  This is, to a large degree, the impetus for this website.  We will continue to post both peer-reviewed studies and anecdotal observations on our blog and on our facebook page dedicated to specific medical conditions that may or may not be related to spaying and neutering.

The one counter argument that consistently raises the ire of those opposed to our views is the issue of overpopulation.  If we encourage people to have intact animals or to delay spaying and neutering, are we in fact contributing to the problems of overpopulation?  I do not want anyone to believe that we are not sensitive to this matter.  We have adopted literally thousands of rescues from our hospitals throughout the years.

Recently, I became open to the idea that there may be an option, at least for male dogs, that offers a solution to both problems.  I have become certified to perform Zinc Neutering , or chemical sterilization.  There is no surgery or stitches and no after-care. (Has anyone wanted to commit hari kari while their pet has worn an E-collar for ten days while there dog continuously tries to mutilate his surgery site?)  It involves two simple injections of a zinc gluconate solution, one in each testicle, that can be done quickly under a light plane of anesthesia.

The procedure is greater than 99% effective at permanently sterilizing male dogs.  Side effects are rare with the most common side effects being irritation or post-injection pain at the site within 3 to 5 days after the procedure.  These side effects are easily managed with post-procedure pain meds.  Most times these pain meds aren’t even required.   Occasional wound dehiscence and absessation has also been reported.

The potential advantage of the procedure, in addition to no surgery, dramatically decreased pain and discomfort in comparison with traditional neutering, and minimal anesthesia, is that dogs retain about 50% of their testosterone levels after Zinc Neutering.  As previously stated in this blog and throughout this website there are dramatic health risks associated with removing a dog’s sex hormones, particularly before maturation.  It remains to be seen once this procedure becomes more mainstream and data becomes available how advantageous is it from a health prospective to retain some of the dog’s testosterone levels.  Will dogs have a more normal and anatomically appropriate skeletal frame?  Will growth plate closure not be delayed to the extent that it is in early s/n animals?  Will behavioral problems associated with low testosterone like submissive urination and fear biting be addressed?  Only time will tell.

Timing of the procedure will also be something that needs to be determined.  Currently it is being used at shelters, often in puppies.  My initial instinct would be to let dogs reach full maturation before doing the procedure.  This approach is potentially problematic in that the procedure is not guaranteed to be successful if testiclar size exceeds 30 mm in diameter.  Again, time will tell….



  1. txchick57 says:

    Interesting! What about cats? I am vehemently opposed to neutering my personal dogs at all (I am not a breeder and my dogs stay indoors and are completely supervised in the outdoors). I also abhor the practive of neutering and spaying young kittens. I find a male cat allowed to fully mature before neutering is a much more interesting personality and pet.

    • Angry Vet says:

      not licensed for cats yet…The procedure would work. Just not FDA approved. I am not sure how intolerable the smell of a male cat’s urine would be after the procedure as compared to an intact cat.

      • CatMom says:

        I have a (mostly) intact male cat, and his urine does not smell intolerable at all. He went through two stinky phases, one at around 10 months, and one at just under a year old. Now I can tell the difference between his urine and the girls’, but it is not particularly strong, and nowhere near what I expected. By the way, he is vasectomised.

      • Susan says:

        Is Zeuterin still available? I just found out about it a week ago. I am rescuing a male dog. I am having him delivered to me on Friday. I was told he looks to be less than 1 year old. The poor guy is missing an eye. I hate to neuter him. Some vets web sites are advertising it. I am in OKC. Any advise on the missing eye will be appreciated as well. Its mostly closed but not all the way. No one knows anything about this dog other then it lived on the street and a old women gave it food sometimes until she moved. It was supposed to be put down so I am taking it.

      • Andree Miller says:

        Come to my house for your ongoing education! That poor kitten was butchered as a two months old when there was still nothing external to remove. I suspect that some tissue remained abdominally so that it behaves and and sound like an entire cat.
        This poor cat has ruined my whole house ,wood floor, carpets leather chairs and all, and it stinks so bad that I bought an industrial ozone machine (I know how to use it) but even this is a placebo since it keeps spraying on!
        The only solution would be chemical castration but it is not “officially” available. I guess federal agencies prefer people to resort to euthanasia! How kind of them. (Perhaps as a template for human usage down the road)

    • Ellen says:

      You are also taking the chance of a male cat beginning to spray and mark territory indoors if neutering is not done prior to this behavior, therefore, people would have to be really on top of things to wait that long.

      Since you are vehemently opposed to neutering your dogs, I have to ask why type of dogs they are and how you fulfill their instinctual need to breed. If this natural desire to mate is left unattended, it can lead to frustration that could lead to aggression.

      • Angry Vet says:

        I have a male dog that IS neutered. It was done at the beginning of my career and was, IMHO, a huge mistake. Interestingly, it was done because my wife was torturing me about him humping the furniture. Well now he has had an ACL surgery, struggles with weight gain (which I do keep in line), and has terrible arthritis. Oh Yea…he still humps!!!

        I will never neuter a male pet of mine again.

        I also have a female dog that is intact. She is in wonderful health (knock on wood).

        • leanne says:

          i have been involved in my (lge size) breed for over 25yrs now only breeding when i want a dog to go on with… total of 5litters.. i have 2 girls in 1 litter (1 intact & other desexed) both have lived life normal and still going strong age of 10yrs old.. i also had a male desexed early and is still going strong both in size and health.l

        • Dottie says:

          I live in the highlands of Panama and sponsor and organize low-cost spay/neuter clinics here. We have an excellent veterinarian who can sterilize 40-plus animals in one day. His incisions are tiny and the animals have never needed to wear an E-collar or have pain meds other than the injection they get on clinic day. And they heal very quickly, certainly much sooner than 10 days.
          Personally, I have reservations about injecting an industrial chemical into a dog’s testicles. And although different opinions exist, it has been proven that sterilizing a dog (male or female) prevents many health problems that could otherwise develop over time…mammary cancer, testicular cancer, etc. I have 14 rescued dogs myself, two of which were sterilized at three months of age. They are now almost 11 and are in excellent health. They still act like puppies.
          By the way, MOST dogs hump, males and females alike (they hump other dogs, not people), even after they are sterilized. It is a domination behavior, not a sexual one. I have one young sterilized female that constantly humps two of my biggest male dogs. She doesn’t give them a minute’s peace.
          And if, as you say, for the injections to work the testicles should not be more than 30 mm. That’s 1-3/16 inches! It seems that would pretty well limit the procedure to puppies.

          • Luta says:

            I just happened upon this and I had my 10 month old Zeutered today. He’s a 77lb GSD and his testicles were only 22/23 mm (well within normal size for his age/breed). Just a layman’s tidbit!

        • Mari says:

          I adopted a Pitt Bull at a local shelter here and they want him to get castrated which I think is a bit extreme, especially if you have him indoors and goes out on your own yard. I think it should be up to owner if he wants to spay or neuter their pet. I have an issue with the removal of testicle and if it needs to be done according to papers I signed then we should have options as well, they gave to me without being neuter because he was sick and had upper respiratory problems at the time to place him under anesthesia. I was tending to his skin allergies or issues as well and told them once he was better I would schedule surgery he is miserable scratching and biting himself and wanted to get that issue cleared before he went under but they claim it can be done and said have until Tuesday 6-14-16 to make appointment or will be issue citations so looking for another alternative and came across your site do you know of a place in or near Palm Beach County Florida where this chemical procedure is being conducted, if not where are you located, can I set up an appointment with you.

  2. Aleta Crosby says:

    How can I find a vet in my area (Tulsa, OK) who is certified to perform chemical sterilization?

  3. It is extremely refreshing to hear a veterinarian speak out against neutering for health reasons. I have chosen not to spay my females after losing one of my Newfs to bone cancer and the other getting two blown cruciates and both with thyroid disease. Though one of my dogs goes through a big false pregnancy and delivery each time, we are fine with her cycle. She is a happy healthy seven year old giant breed. I look forward to your future posts and will direct people to your site.

  4. Jan Goad says:

    As a rescuer, cost is also a factor. So will zinc neutering be less costly than surgery? And will it be difficult to find veterinarians certified in zinc neutering? I’m in a fairly small town between Atlanta and Birmingham. I’m also curious about whether zinc neutering can be done on cats. I’ve been fostering 7 male kittens, now about 5 months old, and they’ve been abandoned by their rescue. I’m on a fixed income and that’s a HUGE expense, relatively speaking, for me to be facing as an independent rescuer, even at the usual $40 per cat. But with everybody full to overflowing, it looks like I’m the only one they have to depend on and I don’t want seven boys spraying my guest room, which is now their bachelor pad. Any thoughts on the matter?

    • Angry Vet says:

      I will have to get back to you on cost comparison. Should be a lot less though, yes

    • Dottie says:

      Veterinarian (and medical) care in the US is outrageously expensive. I expatriated to Panama and I’m a dog rescuer myself, plus I organize and sponsor a low-cost spay/neuter clinic in my area. We hold it once a month and so far we’ve sterilized almost 3,000 dogs and cats. The cost is $25 per dog and $15 per cat. Those amounts include the anesthesia, medications, all supplies, and payment to the doctor. Everyone else is a volunteer. You can see my web site at http://spaypanama-chiriqui.org
      We use very expensive anesthesia because it’s the best and safest, and the animals also receive injections of a long-lasting antibiotic, pain med, anti-parasite, Vitamin B-12, treatment for fleas and ticks, get their ears cleaned and toenails clipped when necessary.
      The vet situation here is awful, though, and I wouldn’t trust my dogs to anyone except the vet who operates at our clinics. I “import” him from Costa Rica. He is the best vet I have ever known, anywhere, including in the US. Besides being very competent he has a big heart and charges less than most because his main interest is helping the animals.
      An example: he repaired a torn tendon on the rear leg of a dog, which was an intricate surgery. He charged the people $130. I read on the internet that the cost in the US would be between $2,500 and $5,000 for that type of surgery. I really don’t know how people can pay those amounts, and how the vets have the guts to charge such outrageous amounts.

  5. Maggi burtt says:

    Hi. I was looking for information on this a few weeks ago, as I knew a dog that had health issues that precluded general anesthesia and neutering without increased risk. My understanding was that it was not done on adult dogs…
    Thanks for posting on it, I think it could be a good thing for people to know more about.
    Also…30 cm? I have yet to see a testicle that is a food in diameter..even on the 170 lb Great Dane I walk. LOL. A typo, maybe?

  6. Mike Braun says:

    Hi Dr. Rob, great blog, thanks. One clarification:
    We tell new trainees to limit the use of Zinc neutering to dogs with testicular sizes (as part of our FDA post-approval study) of equal to or less than 30 mm (not cm). I have injected a number of dogs (Greyhounds and others) in the vicinity of 30 – 34 mm and have caused sterility in all of the injected dogs. Dr. Wang, the inventor and scientist behind Zinc neutering, has assured us that by using the 1.0 ml dosage in testicles up to 35 mm it will cause sterility. We have applied to the FDA for approval to use Zinc neutering in older than 10 month old dogs and in testicles that are larger than 27 mm and hope for an expected approval in February 2013.

  7. Peggy says:

    I have a 10 month old Dane and was wondering if you know if UC Davis does this procedure? In the notes above I see that Mr Braun is applying for older than 10 months old applications. Is it limited to age as well as size? What are the parameters please? Thank you for any info you can give.

  8. Mike Braun says:

    For direct responses regarding any questions concerning Zinc neutering (non-surgical neutering) you may email me at mbraun@arksciences.com. I am one of the Master Trainers for Ark Sciences and will be happy to answer any of your questions.

    • Angry Vet says:

      no Mike…please respond on the site itself…

    • Shari says:

      Yes, PLEASE do answer on line. There are too many people interested in this for you to answer personally, I believe. Also, people who wouldn’t bother to write you may become well informed by reading this discussion.


  9. I really love my pets they are so cool

  10. Red says:

    Thanks for being here. As a Vet Tech and breeder of large breed dogs I am also concerned with skeletal formation and developement. My employer encourages early s/n at six. months to prevent certain cancers of the reproductive organs. I see many dogs come back for orthopedic surgeries and skeletal problems. If I mention waiting to s/n to our clients I would be fired. I am glad that someone is giving this information to the public. I cringe when I see large breeds come in for s/n as pups not fully grown…..I didn’t neuter my male until he was four and he is soooo handsome.

  11. Ellen says:

    Thanks, Dr. Rob, for this post. I recently read about this procedure on Mercola Healthy Pets and was very interested. I really appreciate that you are concerned about dogs’ health and the adverse affects of pediatric spay/neuters. I also like that you are prodding Mike Braun to respond to questions and give more details on this site so we all can learn more about this procedure. I hope that it does get approved for dogs older than 10 months and cannot help wondering why that age was decided upon???

    • Angry Vet says:

      He has assured me that they have performed this procedure many times in older patients and that it is safe and effective

      • sam cucinella says:

        Hi there,
        I am trying to find out if this procedure Will work on a 14month puppy. I couldn’t get him zeutered earlier because he has two major surgeries on his back legs. I don’t want him neutered because of issues with lack of hormones & bone density.
        I have an appointment to get him zeutered but will this sterilize him? Will he need a larger dose? He’s only 14lbs mini dachshund.


    • Dottie says:

      There is 30-plus years of study that proves pediatric sterilization causes few problems. I suspect arthritis and other health problems in dogs were caused by something other than early sterilization. I have LOTS of experience with pediatric sterilization, with my own dogs and with those sterilized at our spay/neuter clinics, and I’ve never known of a problem caused by pediatric sterilization. But each person has to make his own decision about this, of course.

  12. Tegan says:

    I was so excited when I heard about Zinc Neutering, and not even for the reasons you listed here! I see this as an awesome option for management of free ranging dog populations, in terms of a quick and easier solution to setting up surgeries in often remote environments. I also see speed as an advantage in getting dogs in and out of rescue establishments quicker. I didn’t realise the testosterone benefits, so now I’m extra excited on more development of this procedure.

  13. Myra Kotrla says:

    yay yay yay.. still having issues I see with those who believe neutering (cat or dog) will solve all problems. I have female spays who spray! good grief but anyway..
    spayed my last girl early, she was aggressive and too tall.. never again. Getting a puppy, male, want to do chemical neutering. Live in West Texas but willing to travel! How can I find out where to go?

  14. Ulrike Nunn says:

    Hi, my question would be how to include all that into the rescue culture ( for a lack of a better word). Most Non Profits and shelters have a policy not to adopt out without the animal being ” fixed”.
    I for myself would always opt for the healthiest option for my dogs. They are so well taken care of that I can’t imagine it making a difference for me if I have increased responsibilities.
    That being said, that would not be true for most other dog owners ( not here in LA anyway) otherwise the pounds wouldn’t be overflowing how they do.
    The main question is how to promote adopting with the new method ?

  15. Naomi Blake says:

    Thanks for this info – I have adopted a number of young animals from rescues, and they have been spayed at less that 2 months, and I have come to believe it is too early – more intuition than evidence, about general health problems later on, etc. And now science is validating that. Thanks!

  16. Carol Duncan says:

    Are the dogs that receive the zinc neuter procedure usually tattooed to indicate that they have been neutered? If the neutered dog came into a shelter at a later time, it would be a shame to subject him to an unnecessary surgery.

  17. I think the Zinc neutering concept is definitely worth pursuing in male dogs. However, I do want to briefly address the “overpopulation” problem. Why am I putting that in quotes? Because I think much of our supposed overpopulation problem in dogs is an animal rights invention. Absolutely we have too many dogs in shelters. But in the great majority of cases, those dogs HAD homes at some point; the largest number of shelter surrenders are either adolescent dogs or elderly dogs. And statistics show that overall, shelter numbers for dogs have decreased steadily. Some shelters have so few dogs, especially puppies, that they import from other shelters. Some even import dogs from out of the country which I consider a little questionable to say the least. Another indication that we are not overpopulated with dogs is evidenced by the thriving demand for dogs being filled by large commercial breeders. It’s simple economics; demand still exceeds supply. (Cats are a completely different issue and there IS a huge overpopulation issue with cats since they can easily live ferally and can breed much more often).

    I believe in rescue and shelters and I understand why they do choose to alter dogs. I think the Zinc neutering system has some real potential; but I also feel, strongly, that we do NOT have an overpopulation problem. We have a home retention problem.

    • Carol Duncan says:

      I’m not sure where you live, but where I live (Texas), there is a huge overpopulation of unwanted pets. Whole litters of puppies are brought in to municipal shelters, as well as many adult dogs who would otherwise be adoptable. Even the purebreed rescue groups cannot keep up with numbers of dogs that need to be rehomed and/or rescued from shelters before they are euthanized. I volunteer with two purebreed rescue groups and we realized some time back that we could not save every dog that needed help. In addition to the dogs in shelters, we receive several calls/emails every day from people asking us to take their pets because they can no longer afford to care for them. The municipal shelters are begging rescue groups to take dogs because every kennel in their facility is full and they have to make space for incoming dogs.

    • Valerie Masi says:

      Robin, I think you are the only person I have ever heard say we do not have an over population problem. I have been a dog trainer for almost 30 years and in that time I have been employed by shelters as a behaviorist. Every shelter I worked in we would destroy 20-50 animals a day good, sweet, healthy animals because of over population. Our group hosted Zeuterin with Doctor Maas last week in the Coachella Valley and it was great. We did 98 males in 2 days. We have a huge over population problem here because of the Indian reservations and the migrant workers. We have packs of dogs running in the desert. So Robin if you believe there is no over population problem then I invite you here for our next clinic and then tell us how we don’t have an over population problem.

      • We live on an island in the Virgin Islands in the Caribbean where there is a problem with “street dogs”. We have rescued many, but there are always more. We want to start a program with a Veteninary Nurse, working through a local Vet to encourage the people of the islands to have their dogs neutered. I have written to the manufacuters of Zeuterin but to date have not had a reply. There would be no charge for this service, we will purchase the Zeuterin and only ask if they wished to make a small donation to the shelter. Any idea’s ?

  18. Lori Rice says:

    I think the idea of zinc neutering is great, but don’t the testosterone levels remain? I always thought that neutering would remove the testosterone which would “calm” the dog down. If you use zinc neutering would the dog still have the tendancy to roam or be “agressive”?

  19. France says:

    My dog is intact, 3 years old, but one of his testicle is inside. I had no intention to neuter him, but my vet says he has more risks of developing cancer because of that, and that he should be neutered. What would be your opinion ? Thanks!

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  22. Dawn Thompson says:

    Its so nice to hear a vet not advocating for spaying and neutering…particularly pediatric spay or neuter!

    9 years ago I brought a boxer puppy into my home. I had been dogless for 15 years prior, not having been in a position to have a dog due to work, and housing.

    I thought I was doing the right thing by having her spayed at 6 months rather than waiting. Boy was I wrong. I have since read a lot of documentation that shows how detrimental it is to them.

    This dog has gone through so much and I am convinced that her trials would have been less had she been allowed to mature before being spayed or perhaps having a partial spay done where the uterus is taken but the ovaries are left to produce the hormones.

    She needed a TPLO before she was a year and a half (probably because she grew too tall..she is two inches taller than she should be), she was diagnosed as being hypothyroid before she was a year and a half. She started producing mast cell tumors at the rate of 2-3 a year. She has ARVC (probably not related to being spayed, however, I must wonder if hormones play a role in heart health and if she would have not been diagnosed so early with it if she still had hormones in her system), and she has just been dianosed with osteosarcoma.

    All of these things (except the ARVC) All of these things have been shown to be at increased risk for dogs that have been spayed or neutered early.

    Another small study done on Rottweiler bitches showed that that spayed bitches died on average 3 years earlier than intact bitches. For me, with boxers who have an average life span of 8-10, that has huge meaning!

    Spaying and neutering do NOT make one a responsible owner. A responsible owner prevents unwanted pregnancies in their pets regardless of their status as intact or not. I have an intact male and and an intact female in my home and am able to not have unwanted litters. It is easy to do.

    For the next bitch I have, if I do not plan to breed her, I will most likely opt for a partial spay, when she is mature. I dont think I will neuter a dog, unless it is for a medical problem. But for those who do wish to make sure their male cannot sire pups, why not just opt to have a vasctomy….rather than the chemical neuter. I have heard from several people, and have spoken via email lists with numerous others who have reported intense pain in their dogs who have tried the chemical neuter…and several have also reported it is not as effective as they had been told. For those reasons, I think I would opt for a different method if I were going to do something to a male…but in general, I think I will just do a partial spay on the girls, and then after they are mature, and just to prevent pyo, as that is my next biggest worry.

    • Dottie says:

      By a partial spay, I assume you mean a tubal ligation of the female dog. The problem with this is it later makes the ovaries and uterus much harder to find and is thus a much more invasive surgery for the dog.

  23. Linda H says:

    May I make the blasphemous suggestion that in most cases neutering is not called for in male dogs, even for population control. I doubt the wholesale neutering of male dogs has much of an effect on population in dogs. It all comes down to the bitch. If she is spayed or protected during her seasons it doesn’t matter how man intact male dogs are around. If she is unprotected there is a very good chance she will be bred even if 95% of the male dogs around are neutered. If dealing with free-running feral populations resources are always limited for animal welfare organizations. What they have should go to neutering females, not males. That is the only thing that will limit the number of puppies (or kittens) in the next generation.

    I suspect the drive to alter male dogs is an anthropomorphic extension of feminism, which insists that men should be as responsible for birth control as women. I certainly agree when it comes to humans, but it doesn’t extrapolate well to dogs and cats.

    As for my own dogs. My males stay intact and I don’t spay my females until they are at least two years old. I’m not a breeder. I sometimes have both intact males and females, and I haven’t found it all that hard to manage them during heats. My dogs are not small either.

    PS. You should add an archive to you blog to make it easier to get to older posts.

    • Kathy says:

      Good luck my dear. I work in rescue and have heard your story far to many times. “I’ve never had this happen before.” “I had no idea she would have 15 puppies!” and so forth. It’s only a matter of time.

  24. Kelsi P says:

    I really hope zinc neutering goes mainstream. I have great reservations of removing parts from my dog. I have a yellow Labrador who is almost 8 and intact and he is wonderful in behavior and temperament. I now have a younger pup (a mutt saved by my daughter) and I do not want his testicles physically removed. I am trying to find a veterinarian/practice that offers this service somewhere in Northern California, but so far, no luck. However, the pup is only 4.5 months old, so I have quite some time before I have to worry about it… but here’s hoping more and more vets offer this service.

  25. Aussiemama says:

    I have a 21 week old male “mini” Australian Shepard that I will be taking to our local vet for this procedure in a couple days. My husband and I heard about the zinc neutering from a local pet store owner here in Bend, OR and both feel this is a great option for our pup.

    Since our lil guy is starting to display more dominant behavior (ie. humping and growling) while playing with other pups at the dog park, I am interested to see if the zinc neutering will make a difference over time. Regardless, we are happy to not have to deal with or inflict the pain, discomfort and the “cone of shame” that traditional neutering brings upon our pup.

    • Angry Vet says:

      I agree with you on all of the above points. the only “problem” (which I view as a benefit) is that with zinc neutering they maintain 50% of their testosterone levels so the behavioral problems may not abate. I am not a proponent of neutering to control these behaviors anyway, as I feel it is much more important to work through problems of aggression with proper training and behavior modification. Strictly speaking, however, if you were looking for neutering to help with these problems (it’s never a cure all) you would probably do better with traditional neuter

      • Aussiemama says:

        Thanks for the insight about the behavioral problems I mentioned in my last post. Am working with a trainer to help with these issues as our pup gets older.

        More importantly, our lil guy did REALLY well with his zeutering procedure last week. He was a bit groggy from the sedation for the first day but had no issues with throwing up, licking and such. He was back to “normal” the next day, even going for a 3 mile walk with no problems. We’re not thrilled with the rather large (not so well done) green “Z” tattoo on his white belly to indicate his procedure but at least there will be no question in the future. Am hoping the microchip companies will also be able to include the zeuter information in the near future.

        We look forward to seeing how his health and temperment will be affected by this procedure long term. Only time will tell and we are happy to know he’s still intact and will have some hormone function.

        Question, upon speaking with our trainer last night we wonder if there is a “spike” in testosterone right after the procedure until the Zeutrin process (sperm is killed, emptied and scar tissue formed) is complete? Our lil guy seemed more aggressive with other dogs yesterday. Thanks!

        • Olliedog says:

          Just saw your post about your Aussie from a couple years ago – we’re about to bring our 6-month-old goldendoodle to get zeutered, and have noticed (while waiting for his appointment – only available once a month in our area) he’s been demand barking at the ladies more and more. Did your dog’s behavior improve over time?

    • Dottie says:

      As I have posted before, if a competent vet does the neutering there is absolutely no need for a “cone of shame” and for a painful, lengthy recovery.
      Did you read the post from someone here who said: “I have heard from several people, and have spoken via email lists with numerous others who have reported intense pain in their dogs who have tried the chemical neuter.”

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  28. This addresses males being intact although since testosterone is still being produced, you still have sex drive and the inherent possibilities of aggression that can come from a frustrated male. This does not address the females out there still getting pregnant. I work in rescue and the thousands (yes thousands) of dogs and cats euthanized per month due to irresponsible owners is out of control. I’ve had dogs for 50 years, all of which were spayed at 6 months. I’ve never had dysplasia, acl problems, cancers of any type (dispite owning German Shepherds for most of those 50 years) and they all lived to be at least 13 with most 14 and one 15 year old. I still advocate spaying and neutering and probably always will. I’ve spent enough time working at the vet doing emergency spays on dogs with pyometria, breast tumors and the like to not say there is benefit to it as well. As far as humping furniture Angry vet…that’s purely a domination behavior and can be corrected. Neutering an unbalanced dog does not make them balanced. You have to create it prior to that. ACL problem is bad. Very sorry it happened to your dog. My friend’s dog has had both ACL’s replaced and he wasn’t neutered until he was over 3 years old (rescue). He however has pitbull in him which is a breed pre-disposed to the problem due to tibial sloping issues. Late neutering didn’t help him and he’s now recovering from his second ACL tear at 10 years of age. He is a working service dog for her.

    • Angry Vet says:

      Sorry that you disagree but your opinion is valued and welcome on this site. Zinc Neutering does however address the issues of population control so the argument is not valid. As for the rest of your arguments my positions are supported on this site and have references to support all of the others if you wish to see them. Talking about one of your friends dog is also not valid. We are talking statistics. Early Spayed/Neutered dogs are about 7x more likely to have ACL tears. If you want journal articles I suggest you check VIN and Kathi Linn’s work ( a very respected orthopedist). Oh yeah…Trying to dominate the furniture that’s a good one doc!

    • Dottie says:

      Meg, I completely agree with you, and I’ve had similar experiences with early sterilization, both with my own dogs and the thousands that we’ve sterilized at our spay/neuter clinics in Panama.

  29. kat says:

    I wanted to breed from my male cat but he kept escaping his cat run and a neighbour must have chemically treated him somehow to stop him doing the things un-neutered male cats do. I have locked him in securely now for months, and he finally got our female pregnant, but she delivered a single stillborn. Will he ever recover or will we have to keep watching our poor female lose kittens? just telling me where to find info would be helpful.
    btw calcium chloride for male cats seems promising if youre interested in cat neutering too.

  30. Shella says:

    Everyone loves what you guys tend to be up too. This sort of clever work and exposure!
    Keep up the good works guys I’ve you guys to blogroll.

  31. Kate says:

    Hello and thanks for your blog. Do you know of anyone in San Mateo County, California that does zinc neutering? Or anywhere in/near the San Francisco Bay Area?

    • Kelsi P says:

      Kate: I just found out through ARK Sciences that San Francisco SPCA and San Jose offers the zinc neutering. Check them out!

  32. Wow, superb blog layout! How long have you been blogging for?
    you make blogging look easy. The overall look of your web site is magnificent,
    let alone the content!

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  34. Lalonnie Jay says:

    I have a 6 yr old male, he has seizures and has recently shown behavior aggression . I was told nueter him. I can’t find anyone who does the zinc procedure . Where do I go for answers and because he is growling at family members should I nueter him? Please respond ASAP. Thanks

    • Angry Vet says:

      I do the procedure,,,not sure if either trafitional or zinc neuter will help. traditional more likely to help in ths casw

  35. Debi says:

    Victor is a pit bull mix. I have had him since he was 9 weeks old. He is 3 years and 2 months old, and today he was zeutered. I was to pick him up between 3:30 and 4pm, however, when I arrived at 3:30 I was told I would need to wait a bit. At 4:00 I was told it would be about twenty more minutes, that he was coming out of sedation. He was released to me at 4:30 pm. He has pain med Vetprofen 100mg to take beginning tomorrow morning. He is whining, and panting continuously fast and shallow. He continuously is shifting, walking around a bit, and going to a “down” position, not laying on either side. It is clear he is in discomfort. An hour after returning I have become concerned because his panting and high pitched whine continues. I am mostly concerned about the continuous shallow fast pant. It is 6:02 pm. Is this normal, and how long should it go on? Is there anything I can do to give him more relief? Of course I have called No More Homeless Pets and left an urgent message, but have not had any response. Thank you!

    • Angry Vet says:

      panting because he is painful and/or had a bad anesthetic reaction. Occassionally they can be painful for a few days. Occassionally site can absess and surgical removal of the testis is necessary. Needs to be re-evaluated immediately, put on stronger pain meds. PROBABLY will pass in a couple of days regardless but needs to be re-evaluated.

    • Dottie says:

      The surgery was obviously performed by an incompetent vet–and there are a lot of them out there!

  36. Rueben says:

    Its like you read my mind! You seem to know so much about this,
    like you wrote the book in it or something. I think that you could do with some pics to drive the
    message home a bit, but instead of that, this is fantastic blog.
    An excellent read. I will certainly be back.

  37. Lorinda Gayl says:

    We board dogs (spayed and neutered) that play freely in a several acre yard and large indoor area. We used to take intact dogs but found that the un-neutered males drew aggression (and were oftentimes more aggressive, themselves) from the neutered males and even the females didn’t like them much. While I agree with the health reasons for not neutering or at least waiting until a dog is mature, for our purposes intact dogs don’t work. My question is will there still be enough testosterone in a dog’s system after the zinc neutering to attract the above mentioned behavior from the other dogs?

  38. Karen says:

    I live in Oregon and have a 3 mo old Great Pyrenees that I would like to have Zutered. Do you know of any vet in the Portland/Vancouver area that are performing zutering?

    • House of Escobar says:

      Karen, did you ever find anybody in Portland? If so, message my Facebook page “House of Escobar”

  39. Irish says:

    I am very much looking forward to having my 3 y/o Chihuahua “Zeutered” this coming Sunday. I have refrained from having him traditionally neutered because of health issues I’ve seen in other dogs I’ve owned who were traditionally (surgically) neutered. I fully believe that this procedure will be one of the biggest and best things to happen in everyday veterinary work in decades. I’m not a vet, so I can’t say that with any sort of accuracy, but I know that having a less expensive and equally effective sterilization procedure that takes just minutes to perform, w/out need for General Anesthesia, has GOT to be good for shelters, adoption rates, and owners who care about their dogs.

  40. Val says:

    Really? The first red flag should be that it’s “FDA approved.” I dare you to ask ANY “Thalidimide Baby” what THEY think of FDA approved drugs and procedures. Secondly, since the male will retain approximately 50% testosterone, that means they will still be prone to wandering when a female is in heat, still be prone to aggressive behavior, not to mention the high probability of testicular cancer down the road. Sounds like a recipe for disaster. My boys have never had any side effects from being neutered, and that includes my 14 year old Great Dane mix.

  41. charlene Aragon says:

    hi, Do you know of any doctors in the San bernadino county or riverside county area who Zeuter? thanks

  42. daniell smith says:

    Hi. I have a 4 1/2 month old German Shepherd, male. I live in I’ll, just outside of Chicago. When is the timing of the Zinc procedure and where can I try? Thanks.

  43. daniell smith says:

    Hi. I have a 4 1/2 month old German Shepherd, male. I live in I’ll, just outside of Chicago. When is the timing of the Zeutered procedure and where can I try? Thanks.

  44. Julie says:

    May I ask if chemical sterilization is safe for a dog who has a history of Thrombocytopenia? I cannot put my dog under general anesthesia due to the aforementioned problem. He does not receive any vaccines , including the rabies vaccine. Thank you for any information you can provide me with.

  45. Laura says:

    do you know any doctor in Nassau County NY area who use zinc to neuter a dog (only using injection)

  46. Veni says:

    I have a 14 weeks old Great Dane puppy. I have been told neutering is a big NO! Until they are about 1-2 years old. It is said that their bodies need the hormones for their bones to grow healthy.
    Zeuter leaves the hormones right? They still get the hormones they need to grow and developed?
    (I have a lab that was zeutered and I loved the results).

    • Dottie says:

      There are differing opinions (and studies) about “their bodies need the hormones for their bones to grow healthy.” Do your own research, lots of it, instead of depending on what someone else tells you.

  47. Marty Lepkowski says:

    is there any place near The Villages,Fl 32159 that does this type of injection neutering. I’ve been calling but without sucesss.

  48. Marty says:

    Bo is an 11lb 15 month old male toy poodle, do you know where in or near the 32162 area of Florida we can get the zeuterin neutering done. Please respond, I’m at wits end trying to find a place to take him. Thank you.

  49. Marty says:

    e-mail to Mike Braun at mbraun@arksciences.com does not go through, do you know of any locations near The Villages Fl. 32162
    that do zeutering.

  50. lily says:

    I am looking to have my poodle neutered by injection he is older he had 15 teeth removed, becaues of his age i would rather not have it done by slice and dice. I am looking for a vet that will do it. But i live in ontario. asked my he wont do it.
    thank you

  51. mark says:

    I’m trying to find a Zeuterin certificated Veterinarian in NYC… I had no luck in a general Goolge search and the Ark website. Do you know of any in New York City? Also, my dog is 1 year old will they still accept him? Thanks a million!!

  52. Pria Gill says:

    Hello, I currently have a female doberman who is 1 1/2yrs old and what we think is a boxer who is about 5-6monhs. Both are still intact and Ideally we would like for them to stay that way. We keep a close eye on our girl Leila when she is in heat but have been told from several vet’s that Dobermans are predisposed to certain health problems if not spayed. I would like to know if you think the risks out way the benefits of having her partially removed and if you would recommend it, do you know if there is anything in the works for a product like zeuter that would be applicable to females?

  53. Ken Hughes says:

    Hello, Can you tell me when this procedure first became available in the UK? If not the training then when did the drug become available?
    Many thanks for your help.

    Kind Regards,

    Ken Hughes

  54. Pam says:

    I’m in a battle right now with my youngest daughter who recently moved home and adopted a female Great Dane puppy. (What that puppy has done to my house is another story). I have a 7 month old Catahoula male that my husband is strongly opposed to neutering. Now her Great Dane is 9 months old and in heat. We’re keeping the dogs separated (not easy), but she constantly argues that we made the wrong choice by not having ours neutered and says the data for waiting until he’s over a year old is bad science (she’s a Harvard-educated bio-statistician).

    Zeuterin seems like a reasonable compromise, but our vets out here in the boondocks of East Texas have never even heard of it and don’t seem interested in looking into it. I don’t know what to do. Our puppy is happy and easy-going and I don’t want to change that, which I’m afraid neutering will do. I’m very responsible, keeping him in a fenced yard and not letting him run loose to breed with the neighborhood dogs. Should I wait to have him neutered when he’s older than a year old, or is there a vet in Dallas or Tyler who is trained in the use of Zeuterin? I don’t have much time left before he’s too old for that option.

    I know it’s too late for this cycle and that it takes time to take effect, but at least the dogs could be allowed to play together again in a month or two if I get something done. I feel like my husband will at least allow the Zeuterin, whereas having the dog neutered is going to cause problems between us.

    What to do?

  55. Mike says:

    I need to get my large pit bull the zeuterin shot, I’m having a hard time finding someone that does it in my area, I live in Riverside California… Please help!

  56. Janet Smith-Flores says:

    My rescue dog, Kai was Zinc Neutered when I got him. My vet has tried to encourage me to go for the full blown castration and I have refused. I do, however, have two questions. One of his testicles is larger than the other. Is this a function of the procedure? Q2: My neightbor’s dog is in “season” right now and he is losing his mind. (not eating, trying to get out, clawing at the door, howling/whining) Is it possible his procedure did not “take?”

  57. Annette says:

    I’m facing a dilemma. I have a intact make husky he’s ab0ut to be 15 months and i have been hell bent against neutering but recently have a gotten a female Sammi 4 months who is also in tact. I do not want a litter but I have read all the pros and cons. I have schedule both their spayed/neutring next month but I’m still on the fence. After reading your articles Im even more confused! Can you please advise. My local vet has recommended neutrring/spaying.

  58. Kathi says:

    Greetings, There’s no doubt that your blog migfht be having internt browser compatibility problems.
    Whenever I look at your web site in Safari, it looks fine however, when opening in IE, it’s got somke overlapping issues.

    I simply wanted to give you a quick heads up! Besides that, fantastic blog!

  59. Mark Dunigan says:

    What is the difference between chemical neutering testosterone reduction vs. surgical neutering testoterone reduction and will it affect the dogs drive to fight at the same level? In reference to the type of fight drive that drives a dog to continue the attack and not break off? I do a good bit of Pit Bull advocacy work and strongly encourage every owner of this type dog to spay/neuter and cite the reduction in testosterone as one of the many benefits when it comes to the types of serious attacks we often see in the press.I understand there are multiple conditions in all of these incidents and each one needs to be viewed by its individual circumstances but in advocating for this breed type I am also trying to educate owners on anything they might do to reduce the possibility of an incident happening to them.Might seem like a irrelevant question considering the variety of things dogs fight over and that all dogs are individuals but I’m more than willing to be educated or corrected where I may be misinformed.Thank you.

  60. Zofia says:

    Have you or other vets done a follow up exam on neutered dogs to determine and confirm that the testosterone levels are indeed 50% or less as claimed by Ark sciences?

  61. Jill says:

    Thank you for all of the great information. I have an 8 month old yellow lab. I am interested in zinc neutering near Chicago IL
    Thank you!

  62. Chris Webster says:

    I need some help finding a vet who can Zueter my male pit bull. I live in Northern California zip code 95687. Thanks!

  63. Ellie says:

    It is my opinion that we have gone way overboard with this spay/neutering obsession. I rescued a neutered at 6 momths old golden, he died of cancer at six. Was strong armed by a vet to neuter my pup at six months old, he died of cancer at seven. Both dogs also developed hip dysplasia. My next golden was not neutered he lived a healthy disease free life for twelve years. The rest of my dogs throughout my life were never spayed or neutered and lived healthy lives for fifteen to seventeen years, no cancers. I sometimes feel altering is a quick money making scheme.

  64. Holly says:

    How is this procedure compared to neutering with regard to lowering risk of testicular cancer?

  65. Sarah says:

    Can you please send me a link to where you found this information about the testicle size being an issue with zeuterin? I own danes and have never seen that before. “procedure is not guaranteed to be successful if testiclar size exceeds 30 mm in diameter. “

    • Angry Vet says:

      yeah. that is from the company but they have assured me that it is not the case. they just say that because testicles that big were not included in the study submitted to the FDA, but privately they have done plenty that big with no issue

  66. Bern says:

    Hello! We are now in 2016 and zinc neutering has been going on for a few years now yet I can’t find any current info on it. I’m interested to see if there have been lasting negative effects and the levels of testosterone that remains. I have have not heard much talk of a ‘vasectomy’ in dogs…any thoughts one way or the other? I have two 9 mth old huskies and don’t want to castrate them but am interested in sterilization so they can still reap the benefits of testosterone. Either way, I am not prepared to entertain anything until they have reached maturation…my vet was against it but stopped arguing with me once he knew I was responsible and did my homework.

  67. Naia says:

    I have been looking into alternatives to castration for my 7 month old Labrador Retriever. Fortunately, I’ve been able to track down a vet near us (Philly) that performs vasectomies and one that does Zinc neutering. What are your thoughts about these two compared to each other. I am tending towards vasectomy just because that seems to be minimally invasive and leaves him as close to his natural state as possible. He is a very mellow and sweet tempered dog, so I am hoping that he will not start misbehaving as he gets into adolescence. I thought that if there is any reason to remove the testicles or zinc neuter once he is mature, then the option would be left open. I would like to be able to keep taking him to the dog park and to play with other dogs (which he *loves*) and so I must do one or the other soon.

  68. Nanette says:

    We spayed our female shepherd after her 3rd heat. She has become very frail and does not eat. It has been about 5 months. Can we give her anything to get her hormones back on track…..if that’s the problem? We’re going to have blood work done. I truly believe spaying her was the wrong action to take. Any advice would be appreciated.
    Sincerely, Nanette

  69. JayM says:

    We are now into 2017, and Zueterin seems to still be a secret… I have found a single vet that will perform the procedure in the North Georgia area. And the cost – the vet quoted me $280 for a 6 month old Rottie who is around 60lbs. Is there a site with a consolidated list of vets who perform this treatment? I will drive a few hours in each direction if need be… but $280 seems to be high. What are others seeing as far as pricing? Thanks for your replies

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